منابع مشابه
Terrae Incognitae: Integrative Genomic Analysis of Hnrnp L Splicing Regulation
Alternative splicing is a critical component of human gene control that generates functional diversity from a limited genome. Defects in alternative splicing are associated with disease in humans. Alternative splicing is regulated developmentally and physiologically by the combinatorial actions of cisand trans-acting factors, including RNA binding proteins that regulate splicing through sequenc...
متن کامل[Anemia in heart failure: pathophysiology, pathogenesis, treatment, and incognitae].
Although anemia now occupies an important place in our present understanding of the pathogenesis of heart failure, the condition is surrounded in mystery. Anemia is highly prevalent in patients with heart failure and is of great clinical significance. However, the treatment targets for anemia in patients with heart failure have still not been accurately defined. The present article reviews of t...
متن کاملTERRA Incognita at chromosome ends.
Telomeres are transcribed in long noncoding RNA named TERRA. Although TERRA functions have been extensively investigated, the role of TERRA in telomerase recruitment and regulation is still elusive. In this issue of EMBO Reports, Moravec et al report in Schizosaccharomyces pombe that telomere shortening induces the expression of TERRA [1]. They show that polyadenylated TERRA molecules specifica...
متن کاملTERRA: telomeric repeat-containing RNA
Telomeres, the physical ends of eukaryotic chromosomes, consist of tandem arrays of short DNA repeats and a large set of specialized proteins. A recent analysis has identified telomeric repeat-containing RNA (TERRA), a large non-coding RNA in animals and fungi, which forms an integral component of telomeric heterochromatin. TERRA transcription occurs at most or all chromosome ends and it is reg...
متن کاملNurse to Know: Terra Thibault.
What drew you into nursing? (What influenced you to become a nurse?) I guess I took the scenic route to get to nursing. I first started university doing kinesiology. After a year of that I changed my mind and went into architecture. As much as I love and appreciate architecture, I soon realized that I needed to be in health care in some sort of capacity. I went back and did a degree in neurosci...
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ژورنال
عنوان ژورنال: Geograficidade
سال: 2013
ISSN: 2238-0205
DOI: 10.22409/geograficidade2013.30.a12879